Regent Street Cinema is Britain's oldest picturehouse. On 21 February 1896, it became the birthplace of cinema in the UK, when the Lumière brothers used their Cinematographé machine to show the earliest of moving images to a paying audience. Having reopened in May 2015, the staff have been dedicated to engaging with the cinema's groundbreaking legacy, showcasing everything from classic films, internationally acclaimed work and even the odd blockbuster. Karamakate, a warrior shaman and last of his tribe, transcends the worlds of men and seeks truth through their dreams. He alone knows how to find the mysterious and psychedelic Yakruna plant; for some it has life-saving properties, for others it is a commodity waiting to be exploited. Two scientists, in two different times with very different agendas enlist Karamakate on their individual quests in an epic adventure into the heart of the Colombian Amazon to find this mythical plant. Certificate: 12A. Running time: 2 hours 4 minutes.